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Coenzyme Q9研究進展

發(fā)布日期：2017-10-30   瀏覽次數(shù)：0
核心提示：a href=https://www.medchemexpress.com/Coenzyme_Q9.htmlCoenzyme Q9/a產(chǎn)品描述：Coenzyme Qsub9/sub, a nine isoprenyl group-
<a href="https://www.medchemexpress.com/Coenzyme_Q9.html">Coenzyme Q9</a>產(chǎn)品描述：Coenzyme Q<sub>9</sub>, a nine isoprenyl group-containing member of the ubiquinone family, is a normal constituent of human plasma.

<i><b>In Vitro:</b></i> Both CoQ<sub>9</sub> and CoQ<sub>10</sub> are equally cardioprotective, as evidenced by their abilities to improve left ventricular performance and to reduce myocardial infarct size and cardiomyocyte apoptosis. HPLC analysis reveals that a substantial portion of CoQ<sub>9</sub> has been converted into CoQ<sub>10</sub><sup>[1]</sup>. CoQ<sub>10</sub> and CoQ<sub>9</sub> are components of themitochondrial respiratory chain in mammals and can regulate some mitochondrial proteins/functions. Soybean, corn, and rapeseed oils are very rich sources of CoQ<sub>10</sub>, wheras CoQ<sub>9</sub> has been found in high concentrations in corn oil<sup>[2]</sup>.

<i><b>In Vivo:</b></i> The lack of a functional CoQ<sub>9</sub> protein in homozygous CoQ<sub>9</sub> mutant (CoQ<sub>9</sub>(X/X)) mice causes a severe reduction in the CoQ<sub>7</sub<br><br>
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