Nifursemizone 是一種抗原蟲(chóng)藥。<BR><a href="https://www.medchemexpress.cn/Aloxistatin.html">Aloxistatin</a>產(chǎn)品描述:Aloxistatin (E64d) is a broad-spectrum cell-permeable <b>cysteine protease</b> inhibitor.IC50 & Target: Cysteine protease<sup>[1]</sup><i><b>In Vitro:</b></i> Inhibition of protease-resistant prion protein (PrP-res) accumulation in ScNB cells by cysteine protease inhibitor Aloxistatin (E64d) with IC<sub>50</sub> of 0.5±0.11 μM. For the cell surface PrP-sen detection, PrP-sen is immunoprecipitated from media treated with phosphatidylinositol-specific phospholipase C (PIPLC) to release pulse-<sup>35</sup>S-labeled PrP-sen from the cell surface. Aloxistatin is maintained at 15 μM, respectively, in the labeling media of all but the control cells <sup>[1]</sup>. Aloxistatin (E64d) (which specifically blocks cysteine proteases, but not serine proteases such as granzymes) is able to completely block turnover of the CatL substrate Z-Phe-Arg-aminomethylcoumarin, when pre-incubated with NK-92 or YT 5 cells<sup>[2]</sup>. Aloxistatin (E64d) is a broad-spectrum cell-permeable inhibitor of cys<br><br><br><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;background-color: rgb(251,251,251);">公司介紹:MedChemExpress(MCE)專(zhuān)注于各種抑制劑、激動(dòng)劑、API及化合物庫(kù),總部位于美國(guó)新澤西,分別在瑞典和上海設(shè)有歐洲區(qū)子公司和亞洲區(qū)總代理,營(yíng)銷(xiāo)網(wǎng)點(diǎn)遍及全球20多個(gè)國(guó)家地區(qū)。MCE經(jīng)過(guò)多年努力已成為全球生物活性小分子領(lǐng)域的一流供應(yīng)商, 產(chǎn)品涵蓋癌癥、神經(jīng)科學(xué)、抗感染、表觀遺傳學(xué)等20個(gè)熱門(mén)研究領(lǐng)域,PI3K、MAPK等近千個(gè)細(xì)分靶點(diǎn),超過(guò)4000個(gè)活性小分子化合物現(xiàn)貨,以及GPCR、API、離子通道等超過(guò)20種不同類(lèi)型的化合物庫(kù),同時(shí)提供從毫克到千克的專(zhuān)業(yè)定制合成服務(wù)。</span><br style="color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height: 22.0px;background-color: rgb(251,251,251);"><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;background-color: rgb(251,251,251);">MCE 對(duì)每批產(chǎn)品都進(jìn)行嚴(yán)格的LCMS和NMR檢驗(yàn),其產(chǎn)品已被全球近萬(wàn)名客戶(hù)廣泛使用并發(fā)表大量文章、專(zhuān)利;</span><br style="color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height: 22.0px;background-color: rgb(251,251,251);"><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;background-color: rgb(251,251,251);">MCE 定期增加各領(lǐng)域熱門(mén)抑制劑、激動(dòng)劑,不斷擴(kuò)增已有化合物庫(kù),以滿(mǎn)足最新的科研需求;</span><br style="color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height: 22.0px;background-color: rgb(251,251,251);"><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;background-color: rgb(251,251,251);">數(shù)千種產(chǎn)品在上海有充足備貨,24-48小時(shí)內(nèi)送達(dá)客戶(hù);</span><br style="color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;line-height: 22.0px;background-color: rgb(251,251,251);"><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;background-color: rgb(251,251,251);">大量產(chǎn)品提供免費(fèi)試用裝;</span><span style="outline: 0.0px;line-height: 22.0px;color: rgb(62,62,62);font-family: "Helvetica Neue" , Helvetica , Arial , sans-serif;font-size: 11.818182px;background-color: rgb(251,251,251);">已為全球多個(gè)知名企業(yè)、院校構(gòu)建各種定制型化合物庫(kù)。</span><br><br>產(chǎn)品鏈接:<a href="http://www.medchemexpress.cn/Aloxistatin.html">www.medchemexpress.cn/Aloxistatin.html</a><br><br></span><img style="width: 600.0px;height: 310.0px;" src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg" alt="">Purity:98%<BR>MWt:226.1894<BR>Formula:C8H10N4O4<BR>SMILES:O=[N+](C1=CC=C(/C=N/N(C(N)=O)CC)O1)[O-]<BR>Pathway:Anti-infection; <BR>Mechanisms:Parasite ; <BR>Research Area:Infection<BR>電話(huà): 021-58955995<BR>網(wǎng)址: www.MedChemExpress.cn <BR>地址: 上海市浦東新區(qū)蔡倫路720號(hào)2號(hào)樓3層 |
Nifursemizone前沿研究進(jìn)展
發(fā)布日期:2017-11-13 瀏覽次數(shù):0
核心提示:Nifursemizone 是一種抗原蟲(chóng)藥。BRa href=https://www.medchemexpress.cn/Aloxistatin.htmlAloxistatin/a產(chǎn)品描述:Aloxistatin
- 下一篇:暫無(wú)
- 上一篇:Pargolol (hydrochloride)前沿研究進(jìn)展
行業(yè)動(dòng)態(tài)
更多...
- Nifursemizone前沿研究進(jìn) 11-13
- Pargolol (hydrochloride) 11-13
- COX2-IN-1前沿研究進(jìn)展 11-13
- MHP 133前沿研究進(jìn)展 11-13
- WQ 2743前沿研究進(jìn)展 11-13
- Imiglitazar前沿研究進(jìn)展 11-13
- ACAT-IN-1 cis isomer前沿 11-13
- Intoplicine前沿研究進(jìn)展 11-13
- Etonitazene前沿研究進(jìn)展 11-13
- Losmiprofen前沿研究進(jìn)展 11-13