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RG7112
RG7112 is the first clinical small-molecule MDM2 inhibitor designed to occupy the p53-binding pocket of MDM2.IC50 Value:
2015-11-18 10:12 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

3469.00/10mg
010mg起訂

HY-70028
p53 and MDM2 proteins-interaction-inhibitor (racemic) is an inhibitor of the interaction between p53 and MDM2 proteins.
2015-11-18 10:09 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

3580.00/10mg
010mg起訂

Nutlin-3a (chiral)
Nutlin-3 is MDM2 antagonist. 公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動劑、API及化合物庫，總部位于美國新澤西，
2015-11-18 10:07 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1581.00/10mg
010mg起訂

Trabectedin
Trabectedin (Ecteinascidin-743 or ET-743) is a novel antitumour agent of marine origin with potent antitumour activity b
2015-11-18 10:05 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

16740.00/1mg
01mg起訂

3,3'-Diindolylmethane
DIM (3,3'-diindolylmethane), a small molecule compound, is a proposed cancer preventive agent.IC50 Value: 65 uM (SKOV-3
2015-11-18 10:03 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

450.00/100mg
0100mg起訂

Nutlin-3b
Nutlin-3b is a MDM2/p53 antagonist or inhibitor with IC50 of 13.6 M. 公司介紹：MedChemExpress(MCE)專注于各種抑制劑、激動
2015-11-18 10:01 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1451.00/5mg
05mg起訂

Pifithrin-β (hydrobromide)
Pifithrin- HBr (Cyclic Pifithrin- HBr) is a potent p53 inhibitor with IC50 of 23 uM in an antiproliferative assay in the
2015-11-18 09:59 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

3850.00/50mg
050mg起訂

Pifithrin-β
Pifithrin- (Cyclic Pifithrin-) is a potent p53 inhibitor with IC50 of 23 uM in an antiproliferative assay in the human o
2015-11-18 09:57 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

550.00/5mg
05mg起訂

Lenalidomide (hydrochloride)
Lenalidomide (Revlimid, CC-5013) is a TNF- secretion inhibitor with IC50 of 13 nM.IC50 Value: 13 nM [1]Target: TNF-alpha
2015-11-18 09:52 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1534.00/1g
01g起訂

LCL161
LCL161 is an orally bioavailable SMAC mimetic and inhibitor of Inhibitor of Apoptosis Protein (IAP) family of proteins,
2015-11-18 09:51 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1023.00/5mg
05mg起訂

Gambogic Acid
Gambogic Acid activates caspases with EC50 of 0.78-1.64 M and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1
2015-11-18 09:49 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1953.00/10mg
010mg起訂

MIM1
MIM1 is a selective small molecule inhibitor of Mcl-1(IC50= 4.8 uM) that overcomes Mcl-1-dependent leukemia cell surviva
2015-11-18 09:47 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

5000.00/10mg
010mg起訂

Birinapant
Birinapant, a bivalent Smac mimetic, is a potent antagonist for XIAP and cIAP1(Kd value are 45 nM and 1 nM respectively)
2015-11-18 09:44 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

2727.00/5mg
05mg起訂

BV6
BV6 is a small-molecule Smac mimetic, which antagonizes IAP and induces autoubiquitination and subsequent proteasomal de
2015-11-18 09:41 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

3500.00/5mg
05mg起訂

Obatoclax
Obatoclax (GX15-070) is Bcl-2 homology domain-3 (BH3) mimetic, antagonize all antiapoptotic Bcl-2 family proteins (avera
2015-11-18 09:31 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1252.00/5mg
05mg起訂

Costunolide
Costunolide, a sesquiterpene lactone, exhibits anti-inflammatory and anti-oxidant properties and mediates apoptosis.IC50
2015-11-18 09:29 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

558.00/5mg
05mg起訂

HA14-1
HA14-1 is a non-peptidic ligand of a Bcl-2 surface pocket with IC50 of ~9 M.IC50 Value: 9 MTarget: Bcl-2in vitro: HA14-1
2015-11-18 09:27 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

369.00/10mg
010mg起訂

AT-101
AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 M, 0.48 M and 0.
2015-11-18 09:25 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1100.00/10mg
010mg起訂

ABT-199
ABT-199 (GDC-0199) is a Bcl-2-selective inhibitor with Ki of 0.01 nM, 4800-fold more selective versus Bcl-xL and Bcl-w,
2015-11-18 09:24 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]

1989.00/5mg
05mg起訂

Honokiol
Honokiol(NSC-293100), a hydroxylated biphenyl compound isolated from the Chinese herb Magnolia officinalis, has been rep
2015-11-18 09:22 [上海]
上海皓元生物醫(yī)藥科技有限公司 [已核實]